I send cordial greetings to all participating in the Builders AI Forum 2025, taking place at the Pontifical Gregorian University.  I express gratitude to the organizers and all who, through research, entrepreneurship and pastoral vision, seek to ensure that emerging technologies remain oriented toward the dignity of the human person and the common good.

This Forum’s aim of fostering “a new interdisciplinary community of practice dedicated to supporting the development of AI products that serve the Church’s mission” reflects an important issue of our time: not merely what AI can do, but who we are becoming through the technologies we build. In this regard, I wish to note that artificial intelligence, like all human invention, springs from the creative capacity that God has entrusted to us (cf. Antiqua et Nova, 37). This means that technological innovation can be a form of participation in the divine act of creation.  As such, it carries an ethical and spiritual weight, for every design choice expresses a vision of humanity.  The Church therefore calls all builders of AI to cultivate moral discernment as a fundamental part of their work — to develop systems that reflect justice, solidarity, and a genuine reverence for life.

Your deliberations over these two days illustrate that this work cannot be confined to research labs or investment portfolios.  It must be a profoundly ecclesial endeavor.  Whether designing algorithms for Catholic education, tools for compassionate healthcare, or creative platforms that tell the Christian story with truth and beauty, each participant contributes to a shared mission: to place technology at the service of evangelization and the integral development of every person.  Such interdisciplinary collaboration embodies “the dialogue between faith and reason,” (ibid., 83) renewed in the digital epoch and affirming that intelligence — whether artificial or human — finds its fullest meaning in love, freedom and relationship
with God.

With these sentiments, I entrust the work of this Forum to the loving intercession of Mary, Seat of Wisdom. May your collaboration bear fruit in an AI that reflects the Creator’s design: intelligent, relational and guided by love.  May the Lord bless your efforts and make them a sign of hope for the whole human family.

From the Vatican, 3 November 2025

LEO PP. XIV